Neurology

Medical Oncology   

Questions discussed in this category



If so, how long do you continue medication and when do you discontinue? Does treatment with surgical resection versus radiation alone change your mana...

With the recent publication in IJROBP showing a greater than 50% response rate, have you started integrating this into your practice? 

Would you continue KEYNOTE-522 neoadjuvant therapy? The patient has a PMH of sarcoidosis with no stroke risk factors. No residual deficits. 

Do you utilize rituximab or any other specific management strategies?

Is your approach different than that to a primary essential tremor?

History of 4th ventricle choroid plexus papilloma s/p GTR, now with recurrent disease in the 4th ventricle and the left lateral ventricle (7 nodules i...

Are there any protocols in place? Aside from telling patients to use ice packs or bags or immerse hands/feet in ice water baths from 15" before to 15"...

What is your preferred dose/fractionation following a previous course of radiotherapy?

What would be your next treatment for a young adult patient with medulloblastoma refractory to repeat resection, craniospinal irradiation, and initial...

Would the checkpoint inhibitor still work if blocking only that portion of the inflammatory cascade as opposed to more global blockade with steroids?

Based on this review (Melamed and Lee, PMID 31998289), patients with MS on several DMTs may be at higher risk for certain cancers. How does this play ...

Do you prophylactically start all patients on B12, B-complex, and/or omega-3? If so, what dose? What about ice mittens and booties?

Do you ever add prophylactic Keppra (levetiracetam) for glioblastoma patients without a seizure history based on data such as this study (nature.com) ...

Is there role for IVIG? Would you alter the dose or time course of steroid therapy?

In the setting of no personal or family history and no other risk factors for thrombosis, is systemic anticoagulation warranted if local treatments (e...

NCCN lists PCV as category 1 (and now with analysis in Abstract 2002 from ASCO 2019 showing benefit in IDH mutated), and temozolomide as 2B, yet temoz...

Are there contraindications to drugs like oxaliplatin or abraxane? Does chronicity or severity of the patient's underlying symptoms play a role in yo...

For medical oncologists, would you offer a PD-1/L1 inhibitor? For other subspecialties, how would you counsel the oncologist regarding the risk of usi...

For stroke-like migraine attacks after radiation therapy (SMART syndrome), does your management of these patient's change with recurrent episodes? How...

Can you expand on this by sharing exactly what this routine workup should include? What additional tests outside of evaluating for POEMS and amyloidos...

Do you consider the small, but statistically significant, improvement in OS to outweigh the side effects of treatment?

Patients can develop sensory and motor symptoms such as paresthesias, jaw/facial pain and stiffness, cramping and twitching, ptosis and vision changes...


Papers discussed in this category


The New England journal of medicine, 2014-02-20

The New England journal of medicine, 2014-02-20

Neuro-oncology, 2016-09

Onco Targets Ther, 2017 Jan 18

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-01-20

The New England journal of medicine, 2005-03-10

The New England journal of medicine, 2016-04-07

J Clin Oncol, 2012 Oct 15

J Clin Oncol,

Neuro Oncol, 2016 Jul 01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-04-01

Oncol Lett, 2015 Aug 11

N Engl J Med,

Circulation, 2020 Feb 17

N. Engl. J. Med.,

Acta Neurochir (Wien), 2019 Jan 29

J. Clin. Oncol., 2020 Feb 14

Cancer, 2020 May 19

N Engl J Med,

J Clin Oncol, 2020 Jul 14

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-06-20

J Clin Oncol, 2019 Dec 19

Ann Oncol,

Mayo Clin Proc,

Neurol Sci, 2021 Sep 16

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993-03

J Am Heart Assoc, 2020 Nov 23

Am J Hematol,

Arthritis Rheumatol, 2021 Apr 01

Cancer, 2011 Feb 01

The New England journal of medicine, 2018-08-23

Lancet Oncol, 2020 Apr 03

Eur J Cancer, 2021 Sep 15

Thorac Cancer, 2020 Feb 11

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-01

Sci Rep, 2020 Jul 01

Neuro Oncol,

Pediatr Blood Cancer, 2021 Apr 12

Journal of immunotherapy (Hagerstown, Md. : 1997), 2018-05

Neurology, 2019 Mar 08

Front Immunol, 2022 Aug 22

Journal of neuro-oncology, 2012-01

Lancet Oncol, 2021 May 14

Journal of neurosurgery, 2013-04

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-05-01

Cochrane Database Syst Rev, 2020 Apr 28

Cureus, 2022 Oct 24

PloS one, 2017

Circulation, 2016-03-29

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991 Feb

Journal of stroke, 2020 Jan 31

J Clin Oncol, 2020 Jul 24

N Engl J Med, 2023 Jun 04

Journal of neurosurgical sciences, 2019 Jun

Fitoterapia, 2012 Oct 23

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-04-20

Neurosurgical review, 2021 Oct 20

Neurosurgery, 2002-07

Practical radiation oncology, 2013

Radiother Oncol, 2016 Nov 16

Springerplus, 2016 Jan 12

Acta neuropathologica, 2019 Dec 04