Medical Oncology

Triple negative   

Questions discussed in this category



Is there any evidence for sacituzumab govitecan (IMMU-132) in this situation with progressive systemic disease after prior anthracycline and taxane?

Would you consider still immunotherapy even if aggressive disease vs single agent chemotherapy?

Would it affect your decision whether original primary tumor and treatment was hormone positive or negative?

Does the SYSUCC-001 trial presented at ASCO 2020 change your practice?

Patient previously received neoadjuvant carboplatin, anthracycline and taxane regimen and is BRCA negative.

Does the results of the tnAcity trial influence your decision in choosing a 1st line option?

Received neoadjuvant ddAC/T followed by adjuvant capecitabine for residual disease and found to have metastatic pulmonary nodules within months of sur...

Following SRS to the brain lesions, is it safe to closely follow the patient for recurrence?  

Why do the NCCN guidelines suggest using neoadjuvant therapy only for patients with T2 or greater tumors?

Are you using post-neoadjuvant Xeloda based on preliminary data from the CREATE-X trial? Does BRCA mutation influence your decision?

Aside from local therapies (intrathecal, radiation), are there therapies that are known to have better CNS penetration?

(For instance, TCX4 instead of AC->T for smaller tumors?)Does this affect your decision about treating with neoadjuvant versus adjuvant chemotherap...


Papers discussed in this category


ESMO Open, 2016-01-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003-03-15

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-03-10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-08-10

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015-04

Am J Case Rep, 2017-02-28

N. Engl. J. Med.,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-01-01

Breast Cancer Res. Treat., 2014-09-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-06-10

Lancet Oncol., 2014-06-01

Cancer, 2004-10-15

JAMA Oncol,

PLoS ONE, 2016 Oct 14

Sci Eng Ethics, 2017 Sep 15

Lancet, 2015 Mar 02

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-07-01

Lancet Oncol., 2015-03-01

Ann. Surg. Oncol., 2013 Nov 23

N Engl J Med, 2018 Oct 20

Annals of oncology : official journal of the European Society for Medical Oncology, 2018-08-01

Ann. Oncol., 2010 Jan 29

N. Engl. J. Med.,

The New England journal of medicine, 2016-07-07

The Lancet. Oncology, 2018-04

J Clin Oncol. , 2019 Sep 1

J. Clin. Oncol., 2019 Dec 05

The New England journal of medicine, 2018-08-23