Neurology

Neuromuscular   

Questions discussed in this category



Do you switch MG patients from Soliris to Vyzvart due to cost, and with switching do you have a recommended wash out period? 

Is there any role for a surgical intervention in patients with distal weakness, who has marked peripheral neuropathy but also lumbosacral radiculopath...

What is the best way to treat late onset myasthenia gravis (in this case, age >90)? Would the newer complement inhibitors be safe? Steroids in this...

How do you account for a normal EMG/NCS in the setting of prolonged clinical symptoms suggestive of a radiculopathy? How do you explain this to patien...

Are there any environmental exposures you ask about for newly diagnosed ALS patients? 

In patients with hx of metastatic cancer, presenting with unilateral proximal arm weakness. No checkpoint inhibitors use.   Which CSF lab...

Assouline et al., PMID 24411632 recommend delivering 500cGy x 4 fractions = 2000cGy on days 1, 3, 8, 10. Do you follow this schedule, treat every othe...

In patients with suspected CIDP, does the use of imaging—MRI (thickening or abnormal enhancement of cervical/lumbar nerve roots or brachial/lumb...

B5 deficiency can be seen in patients with burning feet syndrome, do you typically screen for this when assessing for neuropathy?

Is there a role for using a trial of pyridostigmine as a diagnostic aid in a patient with suspected (but not confirmed) myasthenia gravis?

In patients presenting with likely statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy - how do you approach the decision re...

How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis, risk of recurrence, and long-term monitoring/treatment?

For patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance, what work up process do you typi...

How do you decide if and when to send patients with AChR+ ocular myasthenia gravis for thymectomy?

I teach my students/residents that they should hardly ever get routine X-rays in patients presenting with radicular symptoms. MRI far better for seein...

How long do you wait (from onset of symptoms) to do a EMG/NCS in a patient with GBS?

Is there is a particular pattern of extraocular motility restriction in Miller Fisher syndrome? 

Given the slow recovery of nerve damage, what would you expect to see on a repeat EMG after treatment? Continued denervation or just sequelae of past ...


Papers discussed in this category


J Clin Rheumatol, 2021 Sep 23

The New England journal of medicine, 2015-10-22

Rheumatol Int, 2019 Feb 18

Annals of neurology, 2013-11

Lancet Neurol, 2018 Mar 07

Pain medicine (Malden, Mass.), 2019-06-01

Continuum (Minneap Minn),

Brain : a journal of neurology, 2016-05

Scand J Rheumatol, 2018 May 18

Clin Neurophysiol Pract, 2018 Apr 05

Muscle Nerve, 2021 May 04

Ann Neurol,

Journal of clinical neuromuscular disease, 2010-12

Lancet,

Lancet Neurol, 2021 Mar 17

Neurology, 2021 Oct 11

Current rheumatology reports, 2015-10

Curr Opin Rheumatol,

Neurology, 2020 Nov 03

Ann Rheum Dis, 2017 Dec

Rheumatology (Oxford, England), 2017-06-01

Autoimmun Rev, 2012 Jul 05

J Immunol Methods, 2016 Feb 18

Lancet Neurol, 2021 Jul

Muscle & nerve, 2010-08

The Laryngoscope, 2016-01

Journal of the neurological sciences, 2011-09-15

J Peripher Nerv Syst, 2021 Jul 30

Neurology, 2020 Jan 20

Eur J Neurol, 2019 Aug 12

J Neurol Neurosurg Psychiatry, 2015 Jan 27

J Clin Neuromuscul Dis, 2018 Sep

Int J Mol Sci, 2022 May 24

N Engl J Med, 2020 Sep 3

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010

BMC Res Notes, 2018 Mar 14

Ann Indian Acad Neurol, 2018 Jul-Sep

Neurol Int, 2014 Aug 08

Diabetes Care, 2002 Oct

Pediatr Blood Cancer, 2021 Oct

Brain, 2013 Oct 26