Questions discussed in this category
Do you switch MG patients from Soliris to Vyzvart due to cost, and with switching do you have a recommended wash out period?
Is there any role for a surgical intervention in patients with distal weakness, who has marked peripheral neuropathy but also lumbosacral radiculopath...
What is the best way to treat late onset myasthenia gravis (in this case, age >90)? Would the newer complement inhibitors be safe? Steroids in this...
How do you account for a normal EMG/NCS in the setting of prolonged clinical symptoms suggestive of a radiculopathy? How do you explain this to patien...
Are there any environmental exposures you ask about for newly diagnosed ALS patients?
Do you see improvement with treatment such as IVIG?
In patients with hx of metastatic cancer, presenting with unilateral proximal arm weakness. No checkpoint inhibitors use.
Which CSF lab...
Will these results change your practice?
Assouline et al., PMID 24411632 recommend delivering 500cGy x 4 fractions = 2000cGy on days 1, 3, 8, 10. Do you follow this schedule, treat every othe...
Is there any data supporting this?
In patients with suspected CIDP, does the use of imaging—MRI (thickening or abnormal enhancement of cervical/lumbar nerve roots or brachial/lumb...
B5 deficiency can be seen in patients with burning feet syndrome, do you typically screen for this when assessing for neuropathy?
Is there a role for using a trial of pyridostigmine as a diagnostic aid in a patient with suspected (but not confirmed) myasthenia gravis?
Does your management change in any way?
In patients presenting with likely statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy - how do you approach the decision re...
How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis, risk of recurrence, and long-term monitoring/treatment?
For patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance, what work up process do you typi...
What referrals do you recommend/imaging orders?
How do you decide if and when to send patients with AChR+ ocular myasthenia gravis for thymectomy?
I teach my students/residents that they should hardly ever get routine X-rays in patients presenting with radicular symptoms. MRI far better for seein...
Is there a role for immunomodulatory therapy?
At what point do you consider genetic testing?
Are there any reasons you avoid therapy?
Are there any alternative treatments?
How long do you wait (from onset of symptoms) to do a EMG/NCS in a patient with GBS?
What other workup/clinical examination findings do you look for?
Is there is a particular pattern of extraocular motility restriction in Miller Fisher syndrome?
What are common side effects to look out for with Eteplirsen?
Ie through electrodiagnostic, imaging, and otherwise?
Given the slow recovery of nerve damage, what would you expect to see on a repeat EMG after treatment? Continued denervation or just sequelae of past ...
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Papers discussed in this category
J Clin Rheumatol, 2021 Sep 23
The New England journal of medicine, 2015-10-22
Rheumatol Int, 2019 Feb 18
Annals of neurology, 2013-11
Lancet Neurol, 2018 Mar 07
Pain medicine (Malden, Mass.), 2019-06-01
Continuum (Minneap Minn),
Brain : a journal of neurology, 2016-05
Scand J Rheumatol, 2018 May 18
Clin Neurophysiol Pract, 2018 Apr 05
Muscle Nerve, 2021 May 04
Ann Neurol,
Journal of clinical neuromuscular disease, 2010-12
Lancet,
Lancet Neurol, 2021 Mar 17
Neurology, 2021 Oct 11
Current rheumatology reports, 2015-10
Curr Opin Rheumatol,
Neurology, 2020 Nov 03
Ann Rheum Dis, 2017 Dec
Rheumatology (Oxford, England), 2017-06-01
Autoimmun Rev, 2012 Jul 05
J Immunol Methods, 2016 Feb 18
Lancet Neurol, 2021 Jul
Muscle & nerve, 2010-08
The Laryngoscope, 2016-01
Journal of the neurological sciences, 2011-09-15
J Peripher Nerv Syst, 2021 Jul 30
Neurology, 2020 Jan 20
Eur J Neurol, 2019 Aug 12
J Neurol Neurosurg Psychiatry, 2015 Jan 27
J Clin Neuromuscul Dis, 2018 Sep
Int J Mol Sci, 2022 May 24
N Engl J Med, 2020 Sep 3
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010
BMC Res Notes, 2018 Mar 14
Ann Indian Acad Neurol, 2018 Jul-Sep
Neurol Int, 2014 Aug 08
Diabetes Care, 2002 Oct
Pediatr Blood Cancer, 2021 Oct
Brain, 2013 Oct 26