Head and Neck Cancers&nbsp;&nbsp;&nbsp;

Is there a role for induction chemotherapy for locally advanced head and neck squamous cell carcinoma prior to definitive chemoradiation?

If you recommend or use induction chemotherapy, what is your preferred chemotherapy regimen?

What is the recommended approach for systemic therapy for patients with locally recurrent p16-positive SCC of the oral cavity who are not candidates for resection or re-irradiation?

What would be the optimal choice of chemotherapeutic agents and duration?

How do you treat SNUC?

Do you prefer upfront cisplatin/etoposide for 2 cycles, then 50 Gy with ENI, then resection, or induction chemo followed by definitive chemoradiation?...

How do you approach a young patient with metastatic poorly differentiated thyroid cancer with rhabdoid/non-anaplastic features?

When would you consider larynx preservation in patients with T4N+ SCC of the larynx?

What is your experience with Gelclair for oral mucositis during head & neck radiotherapy?

In what cases of T3N0 glottic SCC, would you omit chemotherapy and offer radiation alone?

How should you approach treating curable laryngeal cancer with chemo-RT in a patient who had a myocardial infarction during treatment and requires CABG, given the cardiotoxicity of cisplatin and 5FU/carboplatin?

How would you approach patients with high risk mucoepidermoid carcinoma (high grade) of the parotid gland for optimal adjuvant treatment?

Would you prescribe TKIs for Stage IV differentiated thyroid cancer patients who are RAI-naive, with preserved performance status, and are not eligible for surgery?

In what clinical situations do you order NavDx?

How do the results affect your recommendations for workup and management?

What changes do you make in the management of non-endemic nasopharynx cancer compared to endemic?

For example, do you favor using different induction chemotherapy (gemcitabine/cisplatin or TPF) for endemic vs non-endemic disease? Do you favor usin...

Would you recommend lymph node biopsy in a patient with SCC of the right ventral tongue (~1 cm) post excision with close margins and no noted adenopathy on imaging?

Is it appropriate to dose de-escalate in low risk HPV+ SCC of the oropharynx outside of a clinical trial setting?

Such as those meeting the eligibility criteria for NRG HN002, <10 pack years, HPV+ T1-2N1-2b, T3N0-N2b

9 Answers available

How do you consider the role of probiotics for mucositis mitigation in patients receiving head and neck radiotherapy?

In light of the 4/2024 JCO publication by Peng et al., PMID 38215354

Would you offer adjuvant immunotherapy after salvage neck dissection for persistent nodal disease after definitive chemoRT for a patient with p16+ oropharyngeal SCC?

Do you typically recommend avoiding neupogen during radiation treatments?

6 Answers available

In what scenario would you recommend induction chemotherapy prior to chemo-radiation in head and neck cancers and what would be the preferred regimen?

How do you counsel patients and partners of patients with HPV+ cancers regarding the HPV vaccine?

This would apply to gynecologic and GI cancers as well. And as long as the patient's partner is within the recommend age of <45 yo

What are magic mouthwash alternatives that you would recommend?

There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?

9 Answers available

When would you offer post-operative concurrent chemoradiation in anaplastic thyroid cancer?

Would you consider it for a patient with good PS but with limited metastatic disease? What dose fractionation would you prefer?

How do you manage the thickened secretions secondary to xerostomia during head and neck radiation?

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What criteria do you use to determine the resectability of mucosal melanoma of the H&N region?

Is T4 disease a contraindication?

How do you approach cisplatin ineligible patients with bulky EBER positive nasopharyngeal SCC for induction chemotherapy?

Any role for adjuvant systemic therapy for resected sebaceous skin carcinoma?

How do you approach patients with SMARCB1 deficient sinonasal carcinoma for immunotherapy?

What is your approach to counseling patients who require definitive radiation therapy to the head and neck but for whatever reason, cannot/will not undergo recommended extractions?

Do anticipated fields affect whether extractions are required i.e., limited field glottic larynx could forego?

How do you counsel patients regarding timing of dentures after definitive/post-operative H&N radiation with pre-treament tooth extractions?

How do you approach patients with metastatic SCC of the larynx, PD-L1 <1, unable to tolerate 5-FU based chemotherapy due to grade 4 esophagitis/mucositis?

How do you approach patients with locally advanced nasopharyngeal squamous cell carcinoma post induction chemotherapy with gemcitabine/cisplatin and imaging showing mild progression?

Can cisplatin be used again with chemo-radiation?

How do you approach patients with severe mucositis receiving chemo-radiation for head and neck cancer with regards to empiric antifungal or antiviral treatment?

Severe lymphopenia can develop during treatment and increase the risk of Candida/HSV superinfection, along with potential challenges for any procedure...

How do you approach patients with recurrent papillary thyroid cancer following thyroidectomy who now has palpable cervical nodes and underwent neck dissection and RAI?

In a patient with very advanced head and neck cancer treated with induction chemotherapy and then definitive radiation do you recommend adding concurrent chemotherapy with the radiation?

After initial induction chemo, how do you choose between radiation alone or concurrent CRT?

How do you approach patients with node positive sebaceous cell carcinoma of the eyelid for adjuvant chemotherapy and radiation?

How would you approach new dermal mets in a patient who recently finished chemoradiation for head and neck SCC?

In a patient with history of successfully treated locally advanced H&N cancer, how do you discern between a metachronous second primary locally advanced lung SCC vs. metastatic head and neck SCC?

What clinical or radiographic factors would lean you in either direction - ie. time since index diagnosis, distribution or appearance of lung and noda...

What is your approach to treat metastatic poorly differentiated thyroid cancer with papillary features?

Is there any role for RAI?

Do you consider prior use of cisplatin for a previously diagnosed cancer a contraindication for its use as radiosensitizer in a new head & neck cancer?

What precautions, if any, should be instituted with the prior cisplatin exposure?

In patients with nasopharyngeal SCC that have an excellent response to induction chemo, do you alter your chemo-RT dose/volumes in any way?

For example, initial imaging shows numerous bilateral nodal mets extending into the low neck but after induction gem/cis, originally involved nodes ar...

With the current cisplatin and carboplatin shortages, for HPV+ H&N patients with indications for concurrent chemoRT, which agent do you recommend next?

If using cetuximab, would you recommend accelerated fractionation?

What are best practices for oncologists during the national platinum shortage?

Please specify how your institution is allocating resources now or will be soon.

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How are you managing patients with H&N cancers meriting definitive concurrent chemoRT during cisplatin shortages?

Are you waiting until drug availability or changing to a preferred non-cisplatin radiosensitizer? If you're utilizing an alternative to cisplatin, wha...

Would you offer a 2nd generation anti-AR or abiraterone after progression on ADT in patients with metastatic AR+, HER2 expressing salivary gland carcinoma?

How would you recommend proceeding if there are no other actionable variants on NGS?

What are your recommendations regarding sexual activity for a couple when one of them is diagnosed with a HPV-positive oropharyngeal cancer?

How, if at all, does your approach to adjuvant chemoradiation differ with proton beam radiation vs. conventional photon radiation for H&N Cancers?

Is there data on efficacy or toxicity when chemotherapy is added to Proton beam therapy for head and neck cancer like there is data to support adding ...

Do you omit adjuvant radiotherapy in T4a laryngeal SCC with favorable prognostic factors?

According to the NCCN guidelines, there is a highly selected group of T4a glottic larynx patients that can undergo observation instead of postoperativ...

How do you balance aspiration risks with encouraging PO intake for HN cancer patients during and after chemoradiation?

Encouraging aggressive PO intake in patients with swallowing dysfunction may place them at risk for aspiration pneumonia, especially risky if undergoi...

For cisplatin ineligible patients with locally advanced head and neck cancer, would you consider RT + immunotherapy rather than RT + cetuximab?

In light of recent trials showing no difference in outcomes with RT+cetuximab vs RT+IO, does this potentially lead us to use immunotherapy in cisplati...

What methods do you use to prophylactically reduce radiation dermatitis for head and neck irradiation?

Is oral lichen planus a contraindication for immunotherapy in a patient with recurrent oral SCC?

There have been reports of pembrolizumab leading to lichen planus (my understanding is lichen planus pathophysiology unclear, but potentially autoimmu...

In what situations would you place a prophylactic trach prior to radiation for head and neck cancers?

Is day 43 cisplatin 100mg/m2 needed after completion of RT in case of a delay related to neutropenia for locally advanced head and neck cancer?

Should the dose still be given after completion of RT?

Do you routinely use mannitol to prevent cisplatin-induced nephrotoxicity?

If so, do you use it for all patients or only cisplatin doses >= 70 mg/m2? What dose of mannitol do you use?

What criteria does your institution use to indicate patient is ready for PEG tube removal?

What are your top takeaways in Head & Neck Cancers from ASCO 2022?

What were your “top 3” presentations/studies coming out of the meeting this year and how will it impact your own clinical practice...

Do you routinely offer doxycycline or minocycline prophylaxis for cutaneous reactions to EGFR inhibitors such as cetuximab?

If you do not use prophylaxis, what skin care strategy do you employ?

Would you offer adjuvant capecitabine in a patient with nasopharyngeal carcinoma who has had cisplatin - gemcitabine induction followed by chemoradiotherapy with cisplatin?

Stage is cT4N2M0.

How would you approach a patient with well controlled metastatic lung cancer who develops a new primary P16 positive oropharyngeal squamous cell carcinoma?

Is it reasonable to dose de-escalate since survival will likely depend on the metastatic lung cancer?

Would you offer a RET inhibitor for a RET-mutated medullary thyroid carcinoma after R1 resection in a patient with elevated calcitonin?

What factors may favor RET inhibition versus observation?

Would you recommend adding Debio 1143 to high-dose cisplatin chemoradiotherapy in high-risk locoregionally advanced squamous cell carcinoma of the head and neck?

Based on the results of the phase 2GORTEC study reference; Sun et al., PMID 32758455.

Are there scenarios in which you would add nimotuzumab to cisplatin based concurrent chemoRT to treat locally advanced head and neck cancer?

Would differentiating between embryonal vs alveolar rhabdomyosarcoma of the nasal cavity change your neoadjuvant chemotherapy regimen or make you consider neoadjuvant radiation in a locally advanced pleomorphic RMS?

40 yo adult patient with a~6cm mass with concern for skull base bony involvement (group III and stage III, no nodal involvement )

What would you offer postoperatively for a pt with resected 3 separate HPV+ SCC primaries with pN1 disease with ECE who is cisplatin ineligible?

Resected small bilateral tonsil SCC & base of tongue SCC. The patient received 6 cycles of BEP 30 years ago for testicular cancer, and suffers fr...

What is your approach to prescribing gabapentin for oral mucositis prophylaxis during chemoradiation?

Has your practice changed based on the randomized, phase 3 study showing prophylactic gabapentin is not effective? Please share your thoughts and exp...

Does HPV-status play a role in selection of immune checkpoint inhibitors in upfront treatment of metastatic head and neck cancer?

How do HPV-positive patients respond to ICI compared to HPV-negative in your experience?

In which oropharynx patients would you recommend TORS vs upfront RT or chemo-RT?

What clinical criteria would make you prefer TORS as the initial treatment approach?

Would you recommend the addition of chemotherapy in a patient with locally recurrent, unresectable squamous cell carcinoma of the head and neck for whom repeat radiation is planned?

Patient received full dose concurrent cis + RT previously.

How do you approach staging and treatment for a p16+ nasopharyngeal SCC?

How do you stage? Like nasopharynx or p16+ oropharynx? Do you treat it like npx ca with chemo xrt + adj chemo or like opx p16+ with definitive chemo ...

How do you manage anaplastic thyroid cancer that is progressing through radiation therapy?

Assuming a clinical trial is unavailable, would you consider tazemetostat in a patient with metastatic INI1/SMARCB1 deficient sinonasal carcinoma?

Has anyone tried this approach with success?

Would you offer adjuvant chemoRT to a patient who underwent neck dissection for a T0N1M0, p16+ head and neck squamous cell carcinoma?

Lymph node is 4.5cm with no reported ECE. Does the size of the LN or presence or absence of ECE affect your decision?

How would you approach synchronous early stage NSCLC adenocarcinoma and locally advanced symptomatic squamous head and neck cancer that is deemed nonresectable upfront?

Would you prioritize the head and neck cancer or treat the lung cancer first with SBRT to take care of it first? How about if there is mediastinal inv...

What is your preferred approach to adjuvant therapy for a Masaoka Stage III thymic carcinoma after R1 resection?

Would you elect for concurrent chemoRT or RT alone?

Would you recommend induction chemotherapy such as TPF to a patient with locally advanced sarcomatoid carcinoma of the nasal cavity?

Or would you recommend upfront resection as long as borderline resectable?

Are there any circumstances in which you would recommend adjuvant chemoradiation for resected olfactory neuroblastoma?

Is it safe to deliver SBRT with concurrent immunotherapy to head and neck sites of progressive metastatic disease?

What doses and constraints do you use?

Are there any preferred chemotherapy regimens for Stage IV NUT carcinoma?

Is there any role of radiation therapy for these patient for symptomatic relief?

What is your preferred treatment for locally advanced poorly differentiated carcinoma of the nasopharynx with bulky neck nodes that is EBER negative and p16 negative?

Would you consider induction: TPF vs cis/gem or would you proceed with chemoradiation with cis/RT and consider adjuvant cis/5FU?

Do you offer adjuvant androgen deprivation therapy for AR+ salivary ductal carcinomas treated with curative intent?

If so, how do you sequence it? Would you consider before adjuvant radiation vs concurrent with adjuvant (chemo)radiation vs after adjuvant radiation? ...

Is it essential to wait one week after loading dose of erbitux to start RT for head and neck cancer?

In the post-op setting, would you delay 1 week even if it took them out of the 6 weeks post-op window? Meaning the loading dose of erbitux was given d...

For a patient with H&N squamous cell carcinoma who underwent salvage neck dissection for residual disease following primary chemoradiation with weekly cisplatin, do you offer any adjuvant therapy thereafter if extranodal extension is found?

In primary surgical resection, ENE on surgical path would be indication to add adjuvant chemoradiation. After progression through definitive chemoradi...

How would you approach therapy for a nasal high grade neuroendocrine tumor with ipsilateral local cervical adenopathy?

Is the COVID-19 pandemic affecting your choice of high dose versus weekly cisplatin for definitive concurrent chemoradiation for HPV negative head and neck cancer?

How would you treat laryngeal neuroendocrine carcinoma?

If advanced stage do you follow same guidelines as Scc? Do you use same Cth regimen? Role of total laryngectomy ?

How would you approach patient with metastatic anaplastic thyroid cancer with NGS revealing only ARID1A mutation?

When would you consider adjuvant chemoradiation in a patient with esthesioneuroblastoma?

Would gross ENE or R1 resection trigger you to consider adding chemo? If so, do you use weekly cisplatin or cisplatin/etoposide?

Would you offer, and what data would support, the use of an FGFR inhibitor in FGFR3 mutated anaplastic thyroid cancer?

What treatment would you initiate post-operatively for patients with de novo metastatic follicular thyroid CA requiring laminectomy for cord compression?

In addition to TSH suppression, would you opt for RAI, targeted treatment based off NGS, or lenvatinib?

How will your management of head and neck cancers change with the COVID-19 pandemic?

Are you employing more or less primary chemoRT v. surgery for some cancers? Are you dose de-escalating? What are issues radiation oncologists should b...

6 Answers available

How would you approach therapy in a young adult with synovial sarcoma of the head and neck who is not amenable to surgery due to location on the face?

What is your approach in deciding on definitive therapy for locally advanced, HPV-negative head and neck cancer unsuitable for standard cisplatin based chemo?

How do you decide on other chemo regimen? (Dosing, frequency, carboplatin based, non-platinum based etc.) Would you use Cetuximab? Altered fractiona...

For patients with locally unresectable/metastatic head and neck cancer who achieve complete response to chemoimmunotherapy, how do you manage their subsequent care in terms of continuing therapy vs. close monitoring?

For patients with p16+ SCC of a cervical lymph node subsequently found to have an oropharyngeal mass on imaging, is it necessary to biopsy the primary site prior to proceeding with definitive RT?

Is it acceptable to give weekly cisplatin for patients with locally advanced head and neck SCC undergoing chemoradiation?

Is there data to support every 3 week dosage v. weekly? https://ascopost.com/news/march-2022/postoperative-weekly-vs-every-3-week-cisplatin-i...

How do you treat a patient with synchronous locally advanced lung and head and neck cancers?

Does the availability of first line checkpoint inhibitor therapy affect your treatment decision?

How do you distinguish between radiation necrosis, abscess, or disease recurrence in head and neck cancer patients?

Do different modalities of imaging (PET vs MRI vs CT) help you to distinguish one etiology versus the others? What about other clinical characteristic...

How do you manage chronic radiation laryngeal edema for patients treated with RT for a larynx primary in the past?

Aside from smoking cessation, what interventions have you found useful to manage patients with chronic symptomatic laryngeal edema? Steroids seem to b...

Do you give two or three cycles of cisplatin to patients with H&N squamous cell carcinoma receiving chemoradiation with Q3 week cisplatin?

Would you consider low dose lenvatinib or dabrafenib/trametinib for rapidly progressive RAI refractory thyroid cancer with BRAF V600E mutation in a patient in whom you are concerned about tolerance of full dose lenvatinib?

Such as in patients who are elderly or have borderline performance status

How should you manage a coronavirus infected/suspected patient who is receiving radiotherapy and cannot interrupt or delay their cancer treatment?

How would you approach a patient who is receiving chemoRT but has confirmed COVID-19 with minor symptoms, as breaking treatment for 2 weeks quarantine...

7 Answers available

What cisplatin regimen do you prefer with adjuvant radiation in oropharyngeal SCC that is pT4N2 after surgery and bilateral neck dissection?

Is there data for weekly versus every 3 week cisplatin in this setting?

Would you offer adjuvant TKI to patients with locally recurrent multifocal adenoid cystic carcinoma?

For example, for a patient that has been through multiple disfiguring surgeries and radiation and wants to delay time to next resection.

What is your first line therapy for progressive symptomatic metastatic adenoid cystic carcinoma?

Do you start with TKIs or platinums?

For concurrent chemoradiation in head and neck cancers, how important is the timing of weekly radiosensitizing cisplatin early versus late in the week?

Specifically with reference to rural settings where the logistics of early in the week delivery may be more challenging.

How does the management of nasopharyngeal cancer in kids/young adults differ from adult patients?

-The data on induction for adult H&N ca has been mixed (excluded NPX) but recent data suggest a benefit for adult NPX. -Given that this is standa...

Would you switch from weekly cetuximab to cisplatin during definitive chemoRT for locally advanced oropharyngeal SCC?

Patient initially was started on cetuximab due to renal insufficiency of unclear chronicity (uncontrolled hypertension) that significantly improved du...

0 Answers available

Do you always use platinum/5-FU as the chemo backbone with pembrolizumab for recurrent/metastatic H&N cancer?

Although platinum/5-FU was used in KEYNOTE-048, can an alternative like carbo/paclitaxel be given since it may be better tolerated?

How would you manage a local recurrence at the skull base after concurrent chemoRT for locally advanced nasopharyngeal carcinoma?

Given not surgical candidate and within 1 year of chemoRT (recurrence within RT field), would you repeat chemoRT, RT alone, or systemic therapy alone?...

Do you check baseline or surveillance audiometry (if not overtly symptomatic) to screen for hearing loss in all patients getting cisplatin?

Do you offer induction chemotherapy for patients with cT4N0 laryngeal cancer who decline surgery and are not candidates for high dose cisplatin-based concurrent RT?

NCCN suggests either concurrent chemoRT or induction chemotherapy in these patients.

How do you deal with worsening tinnitus in patients on concurrent chemoradiation with weekly cisplatin for head and neck cancer?

In light of recent data from ASCO 2019 and the NEJM, would you recommend induction chemotherapy or an adjuvant approach in combination with chemoradiation for locally advanced nasopharyngeal carcinoma?

Does your approach differ by EBV status?

How soon after ChemoRT for a head and neck cancer can you safely initiate esophageal dilation?

How would you treat a isolated, high grade neuroendocrine carcinoma of the neck with no obvious primary or systemic disease?

Would you recommend surgery, definitive chemoRT, or chemotherapy alone?

For patients with metastatic radioctive iodine refractory papillary thyroid carcinoma that is BRAF V600E mutant and rapidly progressive, would you consider dabrafenib/trametinib combo instead of lenvantinib or sorafenib first line?

Aggressive histology with tall cell variant papillary thyroid carcinoma that's progressed 2 months after RAI and while on TSH suppression, without tra...

What systemic therapy would you suggest for metastatic odontogenic clear cell carcinoma with no actionable mutations on NGS?

0 Answers available

Should upfront neck dissection in head and neck squamous cell carcinoma obviate the need for chemo in a T1N2 oropharyngeal cancer with no ECE?

Some ENTs advocate for a neck dissection as a way to avoid chemotherapy if there is a high chance there is no ECE. This is without removing the primar...

When do you consider upfront surgery for locally advanced (T4) sinonasal CA?

Would you proceed with induction chemotherapy (eg TPF or cis/gem) to downstage or neoadjuvant chemoRT? Would your approach be different if there is or...

How would you approach a locally advanced, radioiodine naive papillary thyroid carcinoma not amenable to a non-morbid surgery?

Have you seen RAI or lenvatinib be efficacious for locally advanced disease — allowing for better surgical outcomes? Do you utilize EBRT?

How would you manage contralateral neck recurrence <6 mos. following resection and adjuvant CCRT for node positive tongue cancer?

If neck dissection was done, do you offer adjuvant chemo and/or XRT?

How do you approach your choice of systemic therapy for relapsed/metastatic H&N cancer (failed definitive concurrent chemoRT) not amenable to further locoregional therapies?

Do you have a time threshold for re-challenge with platinum? Of note, Checkmate 141 defined platinum refractory as relapse within 6 months of pl...

How do you time same-day chemotherapy and radiation for patients undergoing concurrent chemoRT?

For the first treatment day (during combined chemo/XRT courses), is it ok to give XRT first then send the patient for chemo or should the chemo be giv...

If a stage I laryngeal cancer completely responds to FU-based chemotherapy (given for another malignancy) would you consider observation?

What is your preferred radiation sensitizing regimen for cisplatin-ineligible patients with locally advanced unresectable p16+ tonsil SCCa?

How stringent or flexible are you with concurrent chemotherapy and radiation starting on the same day in the definitive CRT setting for HN patients?

Do you ever start radiation +/- 24-48 hrs from C1D1 for chemotherapy due to logistical barriers? Do you prefer chemotherapy to start at beginning of ...

How do you manage small oropharyngeal cancers with N1 or N2 disease?

Is concurrent chemotherapy necessary for these patients?

How would you manage papillary variant squamous cell carcinoma of the oropharynx?

Does papillary histology influence your decisions regarding surgery, chemo, radiation dose or nodal coverage?

When would you use concurrent cetuximab with radiation for a patient with H&N cancer who is not a good candidate for concurrent chemotherapy?

Routinely? Only with oropharyngeal cancer etc.? Given that low expression of EGFR subset did better, do you believe there is a true benefit in cetuxim...

How would you approach distant oligometastatic HPV positive oropharyngeal cancer previously treated with definitive local therapy?

Would you offer locoregional control alone, locoregional with adjuvant therapy, or active surveillance?

How would you treat recurrent parotid gland carcinoma with unresectable, metastatic disease?

How would you treat a patient with head and neck squamous cell carcinoma and adverse features with borderline renal function in the adjuvant setting?

Which of the systemic options would you give concurrently with radiation therapy in the adjuvant setting? According to NCCN guidelines, high dose...

Would you ever NOT recommend adding concurrent chemotherapy to adjuvant radiation in +ECE oropharynx SCC patients who can tolerate it?

In the context of the new staging systems and possible differences of HPV mediated vs smoking mediated oropharynx SCC, would you ever not recommend co...

Do you prefer rhTSH for TSH stimulation instead of thyroid hormone withdrawal when treating patients with radioactive iodine for papillary thyroid carcinoma?

If not, what is your thyroid hormone withdrawal protocol? If so, would you still treat a patient with possibly metastatic disease?

What strategies do you employ to mitigate mucositis related pain during the treatment of head and neck cancer?

While we await the completion of RTOG 1008, what instances do you offer chemotherapy for salivary gland tumors?

What is your preferred first-line regimen for metastatic head and neck cancer?

Do you typically use 5-FU/cisplatin/cetuximab, or do you prefer other options?

Do you transfuse anemic head and neck cancer patients undergoing chemoradiation?

If so, when? Although anemia is associated with worse local control in HN cancer, I don't know of any data that shows that blood transfusions can help...

How do you sequence systemic therapies for recurrent/metastatic head/neck cancer following the recent approval of pembrolizumab?

Do HPV and/or PD-L1 status influence your decision making?

How would you follow patients with differentiated thyroid cancer that no longer picks up iodine after thyroidectomy and RAI, and have thyroglobulin antibodies?

If a patient had a recurrence that was pathologically proven despite negative idodine scans, what imaging scans would you follow up with for surveilla...

Is there data to suggest that definitive chemoradiation to 70Gy vs. postoperative chemoradiation to 60 or 66Gy has any different clinically significant effects on long term swallowing function and other side effects of H&N cancer treatment?

Our ENT surgeons often tell patients with evidence of matted nodes on imaging that their swallowing function will be much worse after 70Gy as compared...

What is your approach for a locally advanced (stage IVA secondary to N2 disease in the neck), HPV-negative, squamous cell carcinoma of the base of tongue in a patient without significant comorbidities?

Definitive chemoradiation vs. surgery followed by adjuvant radiation/chemoradiation?

What criteria do you use for induction chemotherapy in advanced head and neck cancers?

Even though we do not have the best data on the use of induction chemotherapy, what are current practices? Is your practice different between HPV+ an...