Gynecologic Cancers

Endometrial Cancer   

Questions discussed in this category



How do you counsel a pre-menopausal female with endometrioid cancer desiring definitive RT with egg harvesting and IVF for fertility preservation inst...

Insurance authorization for protons is pending, but if the patient cannot have protons would you treat with standard fractionation to ~70Gy or conside...

NCCN recommends brachytherapy plus or minus pelvic RT for surgically staged Grade 1, Stage II patients, but these originally staged IIB patients were ...

For the management of stage II endometrial cancer, NCCN says pelvic RT and/or vaginal brachytherapy.   Do you ever add vaginal cuff boost to pelv...

MRI and cervical biopsy are negative for cervical involvement 

are there any positive or negative synergies from combined megestrol/RT treatment?

At what point would you introduce the discussion of weight management, whether for risk reduction or overall health?

The NCCN recommends either systemic therapy + brachytherapy or pelvic RT + brachy or brachy alone or observation. How do you decide among these option...

Given the recent press release regarding the update on the phase 3 soft tissue sarcoma study of LARTRUVO (olaratumab) showing no benefit to the combin...

Female in her 60s who had presented originally with well-differentiated endometrioid adeno clinically and radiographically involving bilateral paramet...

For a woman with complete resection of serous intraepithelial carcinoma of the endometrium, would you recommend adjuvant radiation or chemotherapy? Wh...

Current NCCN guidelines suggest that vaginal brachytherapy is optional, and there may be concern for over-treatment locally given competing risk of di...

In what situations is it appropriate to offer observation (rather than VBT) to patients with stage II endometrial carcinoma who have had a radical hys...

Would you approach this situation as synchronous primaries (eg. FIGO IA in both) or as a locally advanced endometrial cancer (FIGO IIIA)? What adjuva...

http://abstracts.asco.org/199/AbstView_199_180760.html http://abstracts.asco.org/199/AbstView_199_187537.html  

VC brachy, pelvic RT, +/- chemo?  Does your management change if it is confined to the endometrium without myometrium invasion or if it is only ...

For example, in an otherwise intermediate risk localized endometrial cancer (Grade 2, FIGO IB)?

If the post-operative simulation films reveal a significant lymphocele secondary to pelvic lymph node sampling, is it imperative that the entire lymph...

The gyn oncs at my institution sometimes will not perform lymphadenectomy if biopsy indicates low risk disease. Would LVSI as sole adverse risk factor...

Do you give cuff and chemo or pelvic CRT or chemo alone?

Is there any indication for ENI in early stage disease or in advanced stages, without pathologic confirmation or PET positivity or CT size criteria?

What exactly do you contour and what is your dose constraint to that volume?

Does using something like a vienna applicator allow you to avoid dose escalation with more external beam? How do you recommend doing a classic pa...

Some classic references recommend the coverage of the entirety of the sacrum but the volume delineation guidelines for both seem to only cover the mos...


Papers discussed in this category


Gynecologic oncology, 2004-03

Int. J. Radiat. Oncol. Biol. Phys., 2005-08-01

Int. J. Radiat. Oncol. Biol. Phys., 1990-02-01

Gynecologic oncology, 2003-12

Int. J. Radiat. Oncol. Biol. Phys., 2014-05-01

Brachytherapy, 2015

Gynecologic oncology, 2014-11

Lancet, 2010-03-06

International journal of radiation oncology, biology, physics, 2018-08-01

Brachytherapy, 2019 Sep - Oct

Gynecologic oncology, 2009-10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-01-01

Gynecologic oncology, 2013-10

Gynecologic oncology, 2013-01

Eur. J. Cancer, 2010 Jul 07

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-07-20

Cancer Nurs, 2017-04-21

American journal of clinical oncology, 2018-08

Cancer, 1987-10-15

Gynecologic oncology, 2015-09

Brachytherapy, 2016 Nov - Dec

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014-10

Practical radiation oncology, 2017

Gynecologic oncology, 2018-08

International journal of radiation oncology, biology, physics, 2017-04-01

Gynecologic oncology, 2018-10

Gynecol Oncol, 2017 Aug

J Gynecol Oncol, 2015 Nov 23

Int J Gynaecol Obstet,

Int J Womens Health, 2017 May 02

Radiat Oncol, 2015 Feb 22

Obstet Gynecol,

Annals of surgical oncology, 2016-05

International journal of radiation oncology, biology, physics, 2014-03-15

Brachytherapy, 2015