Hematology

Pediatric Oncology   

Questions discussed in this category


Hydroxyurea is demonstrated to reduce complications and improve long-term outcomes in severe genotypes HbSS and sickle beta0 thalassemia. What clinica...

While L-glutamine has minimal side effects and would likely be added after hydrea, how do you decide between the use of voxelotor and crizanlizumab?

During the Stimate recall, how are we performing DDAVP challenges for newly diagnosed hemophilia A or von Willebrand disease?

Is it at neutrophil recovery, at documentation of CR on bone marrow biopsy, or is there a different point in time?

Assuming CBC w/ different and complete metabolic panel are within normal limits, what (if any) further evaluation or management is needed?

At what age would you treat an early stage hodgkins lymphoma patient with ABVD + RT (adult treatment) vs OEPA x 2 or AV-PC x 3 (pediatric paradigm)?&n...

Guidelines indicate RCHOPx3 +RT as category I and RCHOP x 6 below that; long term f/u for SWOG 8736 showed similar PFS and OS. Do you have and approac...

We often see young women with favorable, early stage disease in the mediastinum who have had a complete response to chemotherapy. With current smaller...

After ABVE-PC X4 and Ifos/vinorelbine x 2 per AHOD 0831 (and is unable to have these sites biopsied), what dose would you treat to and what volume wou...

It seems that with the arms up, you get better lung blocking but with arms akimbo, you might have a lower dose to the humeral head. 


Papers discussed in this category


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-11-10

Practical radiation oncology, 2015

Cancer, 2004-08-15

Br. J. Haematol., 2003-11-01

Br. J. Haematol., 1998-08-01

Cancer, 1990-11-15

Radiother Oncol, 1990-01-01

Int. J. Radiat. Oncol. Biol. Phys., 2017-01-01

Cancer, 1994-01-01

Med. Pediatr. Oncol.,

Arch. Dis. Child.,

Pediatric blood & cancer, 2018-05

Br. J. Haematol.,

Fertil. Steril., 2013 Sep 05

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-09-01

Blood,

J. Clin. Oncol., 2019 Sep 10

Acta Paediatr., 2020 Mar 23

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-07-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-20

J. Clin. Oncol.,

QJM, 2013 Feb 27

The New England journal of medicine, 2007-01-25

Haematologica, 2020

Nature, 2019-03

Blood, 2018 May 02

The New England journal of medicine, 2017-02-02

Blood, 2009 Nov 10